Post on 05-Jan-2016
description
Sociedad Hondureña de Epilepsia
Capítulo de la ILAE
Dra. Claudia AmadorDr Marco Tulio Medina
Dra. Sofia Dubon
The Flag of Honduras
Honduran Epilepsy Society
1. Dr. Claudia Amador * President
2. Dr. Heike Hesse Vice President
3. Prof. Marco T. Medina Past President
4. Dr. Reyna Duron Secretariat
5. Dr. Lazaro Molina Treasurer
HONDURAS
Is a Central America Country with a Population of 8 millions
Health Care Three Health Systems in
Honduras:1. Ministry of Health 2. Social Security for
state workers and others
3. Private Hospitals
Neurological Care
• There was one neurologist per 325,000 inhabitants in 1998
• Neurological diseases account for approx. 20% of the medical consultations in hospitals
Formación de Neurólogos y Epileptólogos WFN
Epidemiología (Medina et al Epilepsia 2003, 2005)
TREATMENT
Status Epilepticus
Proyecto Demostrativo en Honduras: Brecha de Tratamiento
Community Intervention (Medina et al 2010, submitted)
Significant reduction of Epilepsy due to NCC (36% versus 13.9%)
Neuroepidemiology Studies
The Salama Epilepsy StudyETIOLOGY OF EPILEPSY (n=90)
Neurocysticercosis 37%
Cryptogenic (occult) 30%
Idiopathic 8%
Perinatal brain damage 8 %Head trauma 3%CNS malformations 2%Vascular 2%
Other neuroinfections 2%Other causes* 8%
Other causes: inespecific calcified lesions, alcohol toxicity, inespectific intraventricular cyst, multifactorial.
Government involvement
Epilepsy Surgery Program in Honduras
Disease JME CAE
Phenotype
Myoclonic, grand mal epilepsy, 1/3 with absences
Pyknoleptic (2-200/day) absences of
childhood
Pathology Microdysgenesis-Displaced and dystopic cells
Normal
Gene Myoclonin/EFHC1
GABRB3
Transgenic mice
KO mice replicate pathology and susceptibility
KO mice replicate epilepsy
Epilepsy GenesEpilepsy genes found in Honduras
Suzuki et al.Nature Genetics, 2004
Tanaka M, Olsen RW, Medina MT, et al Am J Hum Genet. 2008 Jun;82(6):1249-61.
Medina MT et al. Neurology 2008
Group of Patients
• Epilepsy (FUNDACION HONDURENA DE EPILEPSIA)
Publicaciones (Books and Journals
Latin American Epilepsy Academy (Academia Latino Americana de Epilepsia ALADE) Founded in Sao Paulo Feb. 27th, 2007