I Jornada: “Oportunidades de negocio en nanotecnología”nanotecnología” NanoBioTer®...

I Jornada: “Oportunidades de negocio en

nanotecnología”

NanoBioTer®

Maximizing polymer potential through flexible

nanotechnology

Contents

• About Us

• Technology

• Selected Data

• Production process and Products

Commercial Products

Products in Development

Customer Development

NanoBioTer ® - Material potential. Maximized.

About Us

Mission

To maximize plastics and bioplastics properties through unique, green and cost effective nanotechnology.

NanoBioTer® products

Nano-additives & concentrates for resin improvements (transparency, barrier, mechanical, thermal, rheological and active properties)

“Green” Values and Technology

Food contact approved (Complies with most stringent EU legislations)

Safe handling - nanoscale in only 1 dimension (after dispersion)

Naturally sourced raw materials (Nanoclays)

Focus on sustainable and biodegradable resins

Recyclable (and compostable) product


About Us

Origin - Need for Combined Technologies

Founded in 2004 by Prof. Dr. Jose Maria Lagaron, Scientist with the CSIC, combining technologies from the fields of nanotechnology, food packaging, plastics reinforcement and biobased materials.

2008 - High Growth Company

• Unique patented technology Unique applications

• Group of shareholders composed by venture capital groups,

scientists and business angels.

• High academic level

• International workforce


Structure

Medium Sized International Business

• Commercial Additive Plant - Vall D’Uixo, Spain

Capacity 2,500t/year ( 50,000-150,000t resin/year)

• Commercial extrusion plant – Valencia, Spain

(Under Construction / 2 months)

• Pilot Plants and Laboratory – Valencia, Spain

(Nanotechnology, plastics compounding, microbiology, barrier properties, food contact testing, thermal and mechanical plastics properties)

• Commercial offices: Spain (Valencia) and USA (Boston)


Overview - Nanotechnology

Nanotechnology

nm

DNA

µm

Bacteria Bee Humans

mm m

Definition

Manufacturing of particles, products or devices with controlled particle size,

with at least 1 dimension below 0.1 microns (= 100 nanometers).

Property Microcomposite Nanocomposite

Young Modulus ↑ ↑

Toughness ↓↓↓ ↓ or neutral

Barrier properties ↓ ↑↑↑↑

Temperature resistance ↑ ↑↑

Transparency ↓↓↓ ↓

Cost ↓ ↑ or neutral

Common loading 20-50% 2-5%

Properties

Nanocomposites

Composite materials that incorporate nanofillers, typically below 10 wt.-%. The purpose

of a nanofiller is to enhance target properties while retaining most inherent

characteristics of the original matrix, such as transparency, toughness etc.

Nanoclay Modification

Surface

Modification

Mineral: Natural clay tactoid (stack) Modified Nanoclay

Nanoclay Platelet

Surface modifier

Nanoclay Dispersion

Intercalated Nanoclay Exfoliated Nanoclay

Nanoclay Platelet

Surface modifier

Polymer Chain

Physical Improvement & Active Solutions

Active Species

Nanoclay Platelet

Matrix:

Polymers, Ceramics, Solvents,

Other Substrates

Nanoclay – Matrix compatibilizer

Physical Improvement Active Functionality

Passive Barrier Properties, UV

Blocking, Thermal Properties,

Mechanical Properties.

Antimicrobial, Antioxidant and

Scavengers, Drug Control Release,

etc.

Tortuous Path Principle: Passive Barrier Enhancement

Physical Properties Improvement

O2 O2

Typical Barrier Improvement: Up to 1 order of magnitude

Without NanoBioTer® With NanoBioTer®

Active Properties

Higher efficiency than standard additives due to the exfoliated nano-system

Durability is ensured through permanent modification or controlled release mechanisms.

Without NanoBioTer+® With NanoBioTer+®

Novel properties through functionalization of the nanoadditives

Selected Data

Conventional Polymers and Biopolymers

Oxygen Barrier: EVOH + NanoBioTer®

O2 Barrier

NanoBioTer® decreases oxygen

permeability approx. 70% at

elevated humidity conditions

(m3·m

)/(m

2·s

·Pa

) · 1

0-2

0

Water activity (humidity)

Oxygen Permeability

0

0,2

0,4

0,6

0,8

1

1,2

0,9 0,8

EVOH 32

EVOH 32 + NanoBioTer

JM Lagaron et al., Food Additives and Contaminants, 22 (10), pp. 994-998, 2005

EVOH neatEVOH + 4% NanoBioTer®

NanoBioTer ®: High transparency

Transparency: EVOH + NanoBioTer®

Oxigen Permeability

Limonene Permeability

0

1

2

3

4

1

PET

NanoPET

P(m

3m

/m2·s

·Pa

)·10

-19

0

1

2

3

4

5

1

PET

NanoPET

LT

R (

Kg·m

/s·m

2)·

10

-16

O2 Barrier

PET is generally regarded as highly

sensitive to process conditions and

humidity.

NanoBioTer ® products enable enhanced

barrier properties, when combining

optimum surface modification and process

parameters.

Oxygen Barrier: PET + NanoBioTer®

JM Lagaron et al., Journal of Plastic & Film Sheeting 23 (2) 133-148, 2007

Biopolymers – Definition

Biopolymers (sustainable)

Biopolymers are materials obtained from renewable biomass feedstocks, such as corn, potato, etc., and therefore have a reduced impact in the accumulation of greenhouse gases and on the well-known carbon footprint.

Examples of Biopolymers: PLA, PHB, Chitosan, etc.

Biodegradable polymers

Biodegradable polymers are materials designed to biodegrade into carbon dioxide and water upon disposal by the action of soil microorganisms and water. The degradation must take place in a limited timeframe.

O2 Barrier

PLA

NanoBioTer® enables reduction of

oxygen permeability in the range

of 40-90%. Typical value 50%

improvement.

PHB

NanoBioTer® enables reduction of

oxygen permeability in the range

of 40-90%. Typical value 50%

improvement.

PHB + NanoBioTer® exhibit

barrier properties that are

comparable to PET.

Oxygen Permeability

0

0,5

1

1,5

2

2,5

1

PHB

NanoPHB

PLA

NanoPLA

PET

NanoPET

PHB PET

PLA

P(m

3m

/m2·s

·Pa

)·10

-18

Biopolymers + NanoBioTer®

JM Lagaron et al., Journal of Plastic & Film Sheeting, 23 (2) 133-148, 2007

JM Lagaron et al., Journal of Plastic & Film Sheeting, 22 (4), pp. 265-274, 2006

Transparency: PLA + NanoBioTer®

NanoBioTer ®: High Transparency

PLA neatPLA

+ 5% NanoBioTer®

Thermal properties

2D Graph 6

Temperatura (ºC)

250 275 300 325 350 375

Pé

rdid

a M

asa

(%

)

70

80

90

100 TGA

Temperature (ºC)

Loss M

odulu

s (P

a)

Bioresin

Bioresin 5% NanoBioTer 1

Bioresin 5% NanoBioTer 2

Temperature (ºC)

DMA

NanoBioTer® enables increased HDT (Heat Deflection Temperature) performance in biopolymers

such as PLA*. This is an important characteristic for these materials with generally limited thermal

resistance (softening begins above 40ºC.)

NanoBioTer® delays the onset of thermal degradation, as illustrated by the TGA curve (Thermal

Gravimetric Analysis).

* The exact conditions and improvement is protected under customer confidentiality agreement

PHB blend + 4% market nanoclay

PHB blend + 4%NanoBioTer®

PHB blend

Process Stability

NanoBioTer® has a very low impact on the processing degradation of the

polymer. The polymer structure, as reflected by the melting point, is largely

retained (this is not the case for other traditional nanoclays offered on the

market)

JM Lagaron et al., Journal of Applied Polymer Science, 108 (5), 2787-2801, 2008

UV Protection: PLA + NanoBioTer®

* Patent pending

Increasing Content NanoBioTer®

0

10

20

30

40

50

60

70

80

90

100

PLA Original

Tra

nsm

itta

nce a

t 3

00

nm

( %

)

Transmittance at 300nm (30 microns Film)*

UV Protection

NanoBioTer® has unique, UV

blocking properties.

This technology allows

protection of packaging

contents while maintaining

transparency.

Barrier Coatings

0,0E+00

2,0E-08

4,0E-08

6,0E-08

8,0E-08

1,0E-07

1,2E-07

1,4E-07

1,6E-07

1 2

Biopolymer

standard coating

Biopolymer with

NanoBioTer® coating

Water Vapour Transmision Rate

WV

TR

(g

m /

s m

2)

H2O Barrier

NanoBioTer® is a highly

efficient coating additive.

Example: Water sensitive

protein film.

JM Lagaron et al., SPE Antec 2008 Conference Proceedings, USA, 2008

Antimicrobial additives

High efficiency and duration through controlled release mechanism

Active Properties

NanoBioTer+® Antimicrobial activity tested as per specification in

JIS Z 2801 and ISO 22196:2007 norms.

Without

antimicrobial

additive

NanoBioTer+®

antimicrobial

additive

S.Aureus bacteria

Gelatin film with

chlorophyllin E-140

NanoBioTer® - Process and Products

NanoBioTer® Process

+

Purification

ProcessSurface

Modification

NanoBioTer ®

NanoBioTer ®

Concentrates

Extrusion

Process

Raw Clay Nano Clay

NanoBioTer ® Resin

Products

NanoBioTer® Barrier Additives

• Gases O2, CO2

• Water Vapor

• Aromas

• Migrants

- Up to 1 order of magnitude improvement

Focus systems – Packaging (Food) – Increasing shelf-life

• High barrier / multilayer systems (e.g.. EVOH).

• Biodegradable / Sustainable resins (e.g.. PCL, PHB)

• Coatings (Casting, extrusion coating, lamination)

• Transparent packaging materials (e.g.. PET)

Development Partnership

Efficiency is highly dependent on processing conditions, so materials

should always be tested in the industrial application.

• UV light

• Chemical

• Oil and Grease


Products - Active +

NanoBioTer+® Active Antimicrobial Properties combined with barrier performance for a wide range of applications

• Water and solvent based coatings

• Powder coatings

• Gel coats

• Paints

• Packaging

• Surfaces

Norm Compliant: JIS Z 2801 and ISO 22196:2007


Products – Next Generation

NanoBioTer® Developments

Short term

• Additional active additives NanoBioTer+®

(e.g. antioxidants and other active/bioactive components)

• Additives for a wider range of resins through unique patent-pending modification techniques

• Increased product efficiency through unique patent-pending production steps.

Medium Term

• Reinforcing nanoadditives for resorbable and permanent plastic implants in biomedical applications

• Controlled/accelerated biodegradability


Customer Projects and

Developments

Flexible NanoBioTer® technology

Improvements in an extremely wide range of applications, resins and properties:

• Targeting specific properties for a customer application

• Physical and chemical modification to obtain maximum dispersion in nearly any polymeric system

• Extensive lab and pilot plant equipment for development and testing purposes

Your partner for project management

We work actively with your team to cover all aspects of a successful development:

• Determine objectives and regulatory needs according to application

• Set timing for development steps and milestones

• Identify “what” to measure and “how”

• Determine ownership rights for the developed properties and products

• Finalize project plan and costs

• Create synergies for product marketing and launch


Contact

Business Development DirectorOle Faarbaek Jensen

[email protected]

Research & Development DirectorProf. Dr. Jose Maria Lagaron

[email protected]

Phone: +34 961 31 86 28


Thank you for your attention…

NanoBioTer ®

- Tomorrows Technologies, Combined Today

I Jornada: “Oportunidades de negocio en nanotecnología”nanotecnología” NanoBioTer®...

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